Kassandra visit Greece, as she seek to reunite her fragmented family, dismantle the shadowy Cult of Kosmos manipulating the war, and uncover Isu (First Civilization) secrets, all while wielding a powerful Isu spear and confronting her own destiny.
Isaac Clarke and the crew of the repair vessel Kellion, assigned to the USG Ishimura, a massive planetary mining ship operated by the Concordance Extraction Corporation (CEC) that has gone silent above the planet Aegis VII.
Bounty Hunter has returned, and this time he is tasked with protecting his sister Lizzie from a new and evil threat: RIA Pharmaceuticals, a pharmaceutical giant that is using people to make pharmaceuticals.